Professor Agarwal’s research focusses on extracellular matrix (ECM) remodeling via the collagen receptors discoidin domain receptors (DDRs). We seek to answer fundamental questions pertaining to collagen fibrillogenesis and receptor function at the cell-matrix interface. Our approach encompasses a variety of microscopy techniques to understand the structure and function of the ECM in vascular diseases such as aneurysms and thrombosis. Another parallel vector of our research is to develop novel biomedical applications of the AFM. We have developed many aspects of magnetic force microscopy to study nanoparticle behavior and tissue iron deposits in health and disease. Professor Agarwal has also established and directs a multi-user Bio-AFM core facility at OSU.